3 and 4 are right next to each other in the firing order. If the lifters are good, I'd suspect ignition.
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It may actually be something ignition due to parts availabilty in the country and rushing at the time failing to lookup all the details. It has 0.708" reach taper seat NGK TR6 plugs in it. AFR that uses the same cylinder head casting for their Enforcer calls for a 0.750" reach gasket seat plug. My local Oreilly's has some NGK 6988s on the way for me. Those are a 7 heat range, 0.750" reach Iridium with a projected tip and a 0.044" gap out of the box. Before I dig into it more I am going to try simply installing. The #4 cylinder and #3 cylinder as well as a couple of others all show evidence of fuel glazing. Like they were fouling with fuel and started firing at heavy throttle and baked the fuel and additives on it. Reading about fuel aka high speed glazing it can cause misfiring as well.3 and 4 are right next to each other in the firing order. If the lifters are good, I'd suspect ignition.
Ended up putting Rapidfire 5s in it. They only had 6 of the NGKs show up. NGK makes many of the OE AC Delco plugs. #5 is the AC Delco recomeended replacement for the late 80s and early 90s aluminum head TPI 350. Looks to be a cold plug temperature wise which I need anyway at nearly 11:1.That plug looks like crap, all those specs of junk on it too. I dunno what the NGK deal is. Been running just some plain ol AC delco's in stuff for ages. No problems, the problems usually came when someone put in some fancy pants spark plugs.
The LS is factory, but haven't built an engine that I didn't just vent to atmosphere. There was a PCV thread awhile back. Pretty sure I came across as a planet killing heathen, but its ok.
I want one of those scopes.